| 1. | The effects of metabotropic glutamate receptors in synaptic plasticity
代谢型谷氨酸受体在突触可塑性中的作用研究进展 |
| 2. | Effect of the metabotropic glutamate receptor antagonist on diffuse brain injury through stereotactic injection into brain ventricle
立体定向脑室注射代谢性谷氨酸受体拮抗剂对弥漫性脑损伤影响的实验 |
| 3. | In the human brain, glutamate receptors play a role in several life processes from acquiring and storing memories to possibly contributing to certain mental health ailments
在人的脑组织内，?氨酸感受器影响多项生命功能，例如记忆的形成和储存。 |
| 4. | Recent observations suggest that several subtypes of glutamate receptors are distributed in lung and airway . however there is no report about the effect of glu on alveolar epithelium
近年来一些研究发现在肺泡壁和支气管上皮都有glu的结合位点，但glu对肺泡上皮有何影响尚未见任何报道。 |
| 5. | Moreover, the regulation of growth and development of plants by these glutamate receptor-like molecules certainly is an important target for genetic and molecular manipulation for agricultural improvement
另一方面，科学家亦可利用植物神经介质感受器对讯息传递的影响来操控农作物的发育及生长，达到增加及改善农产的目的。 |
| 6. | More precisely, they block the action of a form of glutamate receptor known as the nmda receptor, which plays a critical role in brain development, learning, memory and neural processing in general
说得更精确些，这些药物阻断了一种叫做nmda型的麸胺酸受体，该受体对于大脑的发育、学习、记忆以及一般的神经活动都扮演著举足轻重的角色。 |
| 7. | These suggest that the inhibition of gaba is a key point in executive control of behavior . the non-competitive antagonist of nmda / glutamate receptors has recently been shown to induce schizophrenia-like symptoms in healthy volunteers and in schizophrenic patients
主要结果和结论如下:一、恒河猴前额叶执行控制功能的行为和生理学特点1.三只猴执行go/n090任务的反应时分别为419士18ms、376士26ms和540士21ms。 |
| 8. | Glutamate ( glu ) is one of the major excitatory neurotransmitter in the central nervous system . the excitotoxicity resulting from overactivation of glutamate receptors is one of the most extensively studied processes of neuronal cell death, and plays an important role in many central nervous system diseases
谷氨酸(glu)是一种重要的兴奋性神经递质，过量的glu释放所致的兴奋性神经毒性在多种中枢神经系统损伤发生发展中的作用已受到广泛重视。 |
| 9. | Excitotoxicity, associated with stroke and neurodegeneration, is triggered primarily by massive ca2 + influx arising from overactivation of glutamate receptor channels of the n-methyl-d-aspartate ( nmda ) subtype . although approaches to treatment of these disorders with antagonists of nmda receptor ( nr ) have been testified to be effective in animal models, successful therapy in humans was limited by the severe side effects of complete nr blockade for their space window and time window
已有的nr受体拮抗剂或阻断剂均为人工合成的小分子药物，能弥散通过血脑屏障(空间窗过大)，作用选择性低，病变脑区及非病变脑区都会受到影响，而且由于神经元可逆性损害的“时间窗”极短，人们难以适时使用有效的神经保护药物，这些均导致已有的药物难以进入临床。 |
